ESR 14: Analysis of thermal enhancement parameters from clinical studies

PhD research

Host: Prof. Oliver Riesterer

Co-PI: Prof. Stephan Scheidegger

Recruiting organisation: Kantonsspital Aarau, Aarau and University Hospital Zurich, Zurich, Rämistrasse 100, 8091 Zurich, Switzerland

Duration: 36 months

Background

Within the HYPERBOOST project, an advanced personalised treatment planning platform for hyperthermia (HT) combined with radiotherapy (RT) based on extensive preclinical and clinical data shall be established. To this end, retrospective and prospective patient treatment data including clinical outcomes for patients treated with combined HT and RT will be derived for modelling and evaluation in the proposed hyperthermia treatment planning system – HYPERBOOST.

Approach 

In this position (ESR14), retrospective and prospective clinical studies will be performed. Retrospective data analyses of the six participating European centers will include correlation of hyperthermia parameters along with related clinical data. Prospective clinical trials with protocols for QA, treatment data and tumor response monitoring will be conducted in cooperation with other HT centers as part of the HYPERBOOST network. Exchange of data between the centers and definition of common strategies for analysis and correlation of outcome data is required. In cooperation with the other working groups of the HYPERBOOST collaboration, the findings will be implemented in simulation models for future HT planning systems.

Our research team

The candidate would be working in the Radio-Onkologie-Zentrum KSA-KSB, Kantonsspital Aarau (KSA), Aarau. KSA is presently the only center in Switzerland having both superficial and deep hyperthermia treatment facilities. As one of the largest radiation oncology centers in Switzerland, KSA combines the highest quality standards and the best possible individual care. KSA participates in national and international networks for clinical studies (including SAKK, RTOG/NRG). One of its important clinical activities is the establishment of a national Swiss Hyperthermia Network Tumor Board in 2014 to discuss treatment options of potential HT patients in an inter-disciplinary Tumor Board. Details of the hyperthermia related activities at KSA can be accessed here.  

Your experience

We seek a highly motivated scientist who enjoys an interdisciplinary environment and an interdisciplinary project, able to work independently but also as part of a team. Candidates suitable for this position are medical doctors with technical interests or physicists with focus on medical physics and interest in the combination of radiotherapy and hyperthermia.

  • Have a Master’s degree in medicine (MD), medical physics (MSc) or related fields
  • Excellent higher education record of accomplishment and strong scientific curiosity.
  • Fluent communication, presentation and written English skills

In addition, the following experience would be helpful, but not essential:

  • Experience in working in a radiation oncology department
  • Experience in hyperthermia - either clinical or research in hyperthermia physics
  • Experience with statistical software packages, namely SPSS or R, along with ability to carry out independently statistical computation and interpretation.
  • Scientific track record.
  • German language skills

Our offer

This 3-year PhD position is funded by the Marie Skłodowska-Curie actions of the European Union's Horizon 2020 research and innovation program under grant agreement No 955625.  You will be appointed as fulltime PhD for 3 years with University of Zurich. The Marie Skłodowska-Curie (MSCA) programme offers a highly competitive and attractive salary and working conditions. The successful candidates will receive a salary in accordance with the MSCA regulations for early stage researchers. Exact salary will be confirmed upon appointment [Living Allowance = €37.320/year (correction factor to be applied per country) + monthly mobility allowance = €600. An additional monthly allowance of €500 is applicable depending on family situation. In addition to their individual scientific projects, all fellows will benefit from further continuing education, which includes internships and secondments, a variety of training modules as well as transferable skills courses and active participation in workshops and conferences.

The combination of RT and HT is a strategic focus of our radiation oncology center and an employment and career development beyond this PhD is envisaged.

Your application

See recruitment procedure. You can apply using the online application form. For more information about the position you can contact Prof. Dr. med. Oliver Riesterer, This email address is being protected from spambots. You need JavaScript enabled to view it., +41-62 838 4249.

Name of the organization

Kantonsspital Aarau, Aarau, Switzerland

(Primary work place, Details outlined in the section "Our Research Team").

University of Zurich, Zurich, Switzerland

(For registration of PhD)